2021-2022学年四川省成都市高新区高一（下）期末生物试卷（附答案详解）

《2021-2022学年四川省成都市高新区高一（下）期末生物试卷（附答案详解）》由会员上传分享，免费在线阅读，更多相关内容在教育资源-天天文库。

2021-2022
ḕᡂᱥᔁI.ᑡᐹᨵᕜḄA.ᱥ!ᾙB.#Ὶ%&C.'()D.*+2.ᙠ“./᪷1ᑖ34Ḅᨵ5ᑖ6”89ᑡ:;<=ḄA.ᑴᱏḄ@A“BCD⁐FGᑴᱏ”B../HI✌ᐜLMᑖ6NLMᐸPHC.⌱RSTUV./ᑮᨵ5ᑖ6ḄᐰYAD../ᜐ[ᑖ6ḄU\ᨎ^ᑮ_`D⁐a3.ᑡᐵ[cdḄe;<=ḄA.fᱥ☠cdᩭciḄᦪk`lmB.n᪶Ḅᑖ6pqr5ᑖ6C.ᓫᱥatYcduvwD.cdᒹyᱥz{ᜓ`ᑖᓄ~SḄYA4.᪷ᓫS+a᜜ᡂ᦮Ḅ஺ᐸ᪷n᪷A.ᐹᨵḄᑖ6B.ᔠᡂᡠ◤Ḅ⏘C.tYᨵ5ᑖ6ᡂD.ᐹᨵ±ᱥlḄᐰᝅ³5.ᑡᔜ⚗⊦ὁᱯḄA.ᑁᑖᔾ¢£᠒B.ᑁᨵ´⏘Ḅµឋ·¸C.⁐¥¦§Ḽ⊦ὁu⌲ª«¬D.a«cᜧºt»ឋᦋ½6.ᱥa¾ᙠ¿ḄÀÁ᜜Â¥)᡾ḄÄᑴVÅᢝᑁÇÈ᛻ḄÊ¿஺ÄaᑁË@ÌÍÎÌDḄḄ\◀tYA.ᑖᓄᡂḄB.⊦ὁᡂḄC.ÐÑᡂḄD.ÒÓᡂḄ7.ᑡ³ÔÕÖᔠ×ḄA.TtB.ccDDeeC.AaffD.GGXBXb8.ᑡឋØÙ[ÚÛឋØḄ)A.ÜÝḄᙊßàáḄâB.ãáḄäàåäC.ᐢḄᮞèàéḄêèD.ë∫Ḅíîàïî9.ᙠÛÚÛឋØḄ⍡ñ89ò,ᜧÝḄôáÛïáÕõឋö÷ḄøùÛúùõឋ஺⌕␺¿ôáᜧÝ`ýøùö÷Ḅ³ÔUþᵨᨬ
Ḅ⍡ᑖA.ஹB.ஹC.ஹD.ஹ10.ᑡᐵ⍡Ḅ┯"Ḅ)

1A.%&'Ḅᱯ)ᩖ+,-ᡂ/Ḅ0123B.567Ḅ8ᵨᨵ;<=ᦪ?C.AB+,CDEFḄᎷAB,HD.ᎷJKLMNOP=ᔠRSDᵫUᔠVḄ+W11.3EYEឋ[Ḅ⍡+,J\]^N_`abᔠ3d1ឋ[ᑖefḄghA.iឋjᔠNkᩖᔠN⊤SḄឋ[amB.N3`noḄKMNJ2qrsMNᦪtYuLMNJvYuC.N3`noḄLMNJ2qrsMNwxyz{KMNwxvyz{D.56|N_`3q}1s~RḄw᳛Yu12.}1sCAaBbkAaBBḄ%ᩖE}1⍡N3`Ḅ}1sqrkV⍡ḄfᑖA.6ஹ1B.6s1C.8ஹ1D.8ஹ2484813.Y⁐ky⁐q≆≈⁐RḄ3Eu}1Lឋᨵ⁐k⁐Kឋᨵ⁐஺ᑡᩖUᔠJᐸN`⊤SsᑨឋḄA.?yyxdyyB.,YyxgyyC.9yyx^YYD.$YyxjYy14.«T®S᳝±²᳝±ᩖ³`J«®ᓰ:ஹ«¶®ᓰ2ஹ88«®ᓰ:ஹ«¶®ᓰdᑣ¸¹Ḅ}1s88A.ttSsxTTSsB.TtSsxTtssC.TtSsxTtSsD.TtSsxttss15.ᙠ½⁵⃅J}1sCCCḄÀÁÂÃ&ccḄÀÁÂ&CcÂ'Ã&஺ᙠᑡᩖUᔠJÂÃ&ḄfᨬḄA.CCxccB.CcxCCC.ccxCcD.CcxCc16.ᱫÆ&ḄÇNᨵÈÉÇkÊËÇqqNᨵÌ⁐k⁐qᔜÎ3Eu}1Ïᑴ஺SᵨjqḄÈÉÇ⁐qNkjqḄÊËÇÌ⁐qNÑC¸¹ABᩖᑮḄBCÈÉÇÌ⁐qN஺BF2,=Ôbᔠ}1ḄᵫUᔠV஺ᑡEF2ḄÕÖJ┯"ḄA.F2Jᨵ9q}1s4q⊤SsB.F2JÌ⁐qN²⁐qN2fC3d1C.F2JSḄ¸¹ᡠØᨵḄឋ[UᔠᓰÙD.F2JÈÉÇ⁐qN~RḄ}1sᨵ4q17.ÛUABឋ[ᑖefÜÝ+,|ᔣᵬஹà~Û᫜ᑁᔜãᐭ20~ᐸJ10~᪗çD,10~᪗çduᜧḄRÜséêᒴᯠ³ᑖᵬஹà᫜ᑁOPᢕî1~ÜsçïUᔠðñ᫜ᑁÜsᐰóᢕô஺õ56öSUᔠ=ÔDDdDddddau1d2d1஺ᑡ÷ø²ᑖ᪆aᔠᳮḄû2⚓ᐳ32⚓

2A.þᐸJ3᫜ᑁḄDkdᔜÿ10
ḄᦪᓿḄB.ᣚᩞஹᜧḄᳫᐙᑖ#ᒴ%&'()C.*+ᢕ-./0ᢕ-Ḅ123᫜56*78ᢕ-Ḅᭆ᳛;D.ᢕ.123᫜᤯ᒴ=>50100+஺56᪵AᦪBCᜧDEFG()18.DᦪᑖHIJK*
LᑖᐹᨵOQA.4
ḼSTB.4
DNAᑖC.2ᩩVWX⁐ᓫD.2[X⁐19.\]^∫Ḅ`aᑖHᐸᑁḄdᑡKfghᨵiᩩjX⁐ḄkOQA.lmnB.ᨵSᑖHKoḄ3C.+mnD.ᨵSᑖH.oḄ320.dᑡᐵq⍡stuv=⌕xyz{Ḅ|}┯(ḄkOQA.ᵨtᑖ᪆FG^⍡sB.ᵨDNA[C.⃬ᵨᳮ“ᙠX⁐v”ḄᎷ¥D.᥅᪷;qឋ©ªឋ«Ḅᐵὶ6ᙠX⁐v21.᝞⊤°^∫\fᩩX⁐vḄ±
dᑡ|}`²ḄkOQ1IIIIIIIIII11IIII1³´᜜¶ᩋ¸¹º»¼½W¾¾©¿ÀIIP.nr.¼Á¼A.^∫ḄᐰÃÄÅqX⁐vB.ᩋ¾¼ᙠKÆÇÈᙠ4
C.K´¼ªᩋ¾¼k;ÅD.ÉÊKËÆÇÌÈᙠ´¼ªᩋ¾¼22.᝞\ÍÎKᵫf[;ÅÐᑴḄ⍡sÒḄ⍡sÓ஺dᑡᐵᑖ᪆┯(ḄkOQÔh-OEZhrOÕ`”ឋA.Ö×Ò´ᓄÒᑣn-6ªn-7ḄḄᭆ᳛:B.Ö×Ò¾Û⁐Üᑣm-9ḄÝÒᩭß1-2

3C.ÖI-2I-4ækçÒ
ᑣ×ÒᢙéÉêDìíÒD.Ö1-1ஹ1-3H-8ækçÒ
ᑣ×ÒòjX⁐⍡sÒ23.óôõḄឋ«ögkZWù7úûõOZBZBQªýúûõOZbWQÿ,R,BF2ឋḄA.31B.21C.11D.12124.⍡$ឋᾯ&'()*+,-./0X2ឋ⍡$3஺53⍡$ᱯ78ᒹ:A.ᵱឋ<ὅḄ᝕?ᐰAB3B.᝕ឋ<ὅC/ᵱឋ<ὅC.D3EF⊤HI◞K⍡$D.ᵱឋ<ὅḄLMEF<ὅ25.Oᑡᐵ/“STUVWXTḄYZ”Ḅ\]^_ḄA.◤ᵨbcdᨵ32Pg35sḄSTUVWᜧjᩚTB.5YZlmnᜧjᩚTḄ⍡$ᱥpDNAC.ᤅsIntᜧjᩚTᑁḄSTUvwxᩭD.z{In|}~ḄᜧjᩚT26.Inm⍡$ᱥpnᳫTḄU᜜ᓄYZ஺Oᑡ⌱⚗ᡠᑡḄYZᜐᳮ~ᨵᐝTḄA.S*TḄp+R*TB.S*TḄC+R*TC.S*TḄC+S*TḄp+R*TD.S*TḄDNA+R*T27.¡DNAᑖ£d150¥¦§¨©ª«¬AḄᦪ®ᓰ30%,ᑣ²³¬GḄᦪ®A.30¥B.40¥C.50¥D.60¥28.OᑡᱥUᑁ᪶⏚ᑖ£C᪵ឋ¹ᐵḄA.¦§ḄᦪºB.᪶ᵞ⏚Ḅ᣸ᑡ½¾C.᪶ᵞ⏚Ḅ¿ÀÁÂD.᪶ᵞ⏚ḄᦪºCÃ29.᝞ÆI{Çᑣজঠ⊤ÊᳮËÌ஺Oᑡ\]^_ḄA.জ⊤ÊDNAÍḄËÌB.ঝËÌᨵ¦AU§C.ঞটÒ◤⌕IRNAÕD.T2STUVWXTËÌ×BঠËÌ30.Oᑡ./DNAḄØ×ḄজÙÚ⍡$ÛÜঝÙÚ⍡$Ýṹঞ×ÍxmRNAট×àᐭ᪶Uâ4⚓ᐳ32⚓

4ঠ×åæç⏚ড×éᑴpḄᔠᡂ.A.জঞঠB.জঞডC.ঝটডD.ঝ©©31.§/᝞Æ⊤ÊḄᳮËÌᨵᐵíÇ^_Ḅᨵজ⊤ÊDNAîᑴËÌঝ⊤ÊÍËÌঞÆᐳᨵ5ï¦টÆᐳᨵ8ï᪶ᵞ⏚ঠÆᐳᨵ5ï᪶ᵞ⏚ডÆḄAᙳK⊤bñï᪶ò⏚.DNA•••A—G-C—T•«•••RNA…U--C—!ñA.জঝঞB.টঠডC.ঝঞটD.জঞ©32./§óᱥUឋôᐵõḄᳮöᑨøOᑡ⊤]^_ḄA.ᱥUḄឋôù⌕ᵫóûFḄB.üïឋôÒᵫñ¥ᱯFḄóûFḄC.óÒýËéᑴ⏘ḄᔠᡂᩭéᑴឋôḄD.óḄ¦¾ᑡÿ
Ḅឋ33.202111ᨴ9,ᙠᓭᑮḄ
202111ᨴ26
!"#$%&ᐸ()ᝍ+,-
ᐹᨵ᩽1Ḅ23ឋ஺ᝍ+,-Ḅᩭ678:A.;$B.<C.3⁐>?᪀D.3⁐>ᦪB34.CDEF#GB?HIJKLM⌼⊈PQRSTUVWXY
Z[\]ᐰ!_ᨵḄ`abcdef#RSឋg⊈஺V
hὅḄSLC52A2j#k<
LMF#GB2HIJK
hὅᙠlᢝnᵨF#GB2pqᨴr
⌼⊈PQTUVWX⌲tឮvwY஺xᑡz{w[Ḅ78:A.hὅ◤}~nᵨF#GB2■g⊈vjB.ḄៜF#GB2vSLC52A2<C.Ḅ>dej#Ḅ<ᐹᨵឋD.SLC52A2ᑭᵨkDNAᑖᐹᨵ᪵ឋḄᱯ35.᝞ᡠ]ᙠdeᑖ3⁐>Qj#Ḅ
জঝQLMḄ¡¢78:

5A.3⁐>᧕¤ஹ<B.3⁐>᧕¤ஹ;$C.;$ஹ3⁐>᧕¤D.;$ஹ3⁐>¦ᜫ36.202110ᨴ
ᡃ©ᙠ“U«ᓝ®”°±³´°k3000µ¶·¸ᐭº»
¸¼½ᜩ¿ḄẆÁ஺xᑡz{w[Ḅ78:A.¸ᐭº»Ḅ3000µ¶·ÂÃj#⍡2B.¶·Ãᙠº»ᱯᨵÅ᛻ḄÇLxj#;$C.´°Ḅ¶·È7ÉjḄÊËD.¶·ÌᨵÍᑖÃÎ#⚜ÐḄÑÒ37.xᑡᨵᐵ#ᱥḄÕ
w[Ḅ78:A.C#ᱥ>ᑁCᩩ3⁐>³kØqᡈÚkØq
ÛᓄÝÞ3⁐>ᦪBḄB.ßᙊáâxãäáâãᙊáâ
Ûᩭ6Þ<C.DNAᑖÌåæḄçèஹ¦ᜫTéᣚëÂ7<D.ìHíH
HíHkᔜï
7]ðñòó̸¼k;$38.CôõD$æöᓄḄ⍡2÷øTj᳛¸¼úû
xᑡᐵz{w[Ḅ78:A.úûöᓄḄ⍡2÷ø◤ᙠüÌýþúûB.úûöᓄḄj᳛◤ᙠÿ
C.ᙠḄD.ᓄḄ᳛=ὅᦪ/!Ḅ"ᦪX100%39.#$%&'ᙢ)ᩭ+,-.▾01⍡345Ḅ678ᝣ:;஺=ᑡ?@┯BḄCA.$DCᔲFGᝣḄ⍡3ᱥIஹKLM;NOPᨵᐵB.F〉78ᝣTU+678ᝣᡠWX᝕Ḅᐜᜩ\]W᳛^6C.⍡345_8,`aCb⍡3cdஹ⚜■_gᶭḄi⌕klD.ᓽnopq$DrstuO+v$Dwᨵxy⍡340.z{ᑭᵨ~P⃉Ḅ
+⌱50⃉+)~PᜐᳮḄ+ᑮ᝞ᡠ+TᐵpḄC¡£¤6⚓+ᐳ32⚓

60.05%^
ᜐᳮ0.1%
ᜐᳮ
ᜐᳮᜐᳮ/dA.ᵫxªᜐᳮ«¬®;Ḅ¯°᳛B.O°²C;Ḅ¯°᳛+³°²C~Pᜐᳮ«C.µᳮC~Py¶ᢓᑴ¹┴Ḅ»ᡂ+¯½»ᡂ;D.ᑨaC⃉ᨬx☠ḄÂCÃÄÅÆᑖÈ
ÉḄÊ⁐ᦪ41.NÎÏᱣÑ_NÒÑᐹᨵᓝᑖÕ⌕ḄÖ×஺ØÙ᯿⊤
ᑁÝÞᡂ=⊤:NᩖᯰuOæçᓫN(1)______NÂNNNi⌕⍡3uOÕ(2)(4)(3)______¡ᶍ£èµᳮᩖá->(5)ìᵨñT毡ᶍ£¡ᶍ£(6)______¡ᶍ£Â½Ê⁐óô⌱úûüý+þᱏஹ
(7)ᜧ⃩ᨬᜧ(8)______¡ᶍ£ᱥḄᨵᡠᶍö÷42."#$%ᩖ'()Ḅ*+஺$%-./0ᑖ2ᨵ3243146⁐-஺8ᵬஹ:ஹ;⊤=%Ḅ>?./ᙠABᑖCDEḄFᑖ6⁐-Gᡂ8IJ./ᑖCKLMᩩ6⁐-ODNAᦪḄTᓄ஺᪗ᩩ⁐ḄDNA°ᑖ1;./ḄVW#
:./ᜐY8IZ[0\஺28IZ[0de\_ᡂḄ`a#஺3bᵨMᓛ$Mᓛ%efgᓛ"hi"⊤jkᔜAmB஺nop“r

7_ᡂ”hMt☢v⌕ᭆy⍡{g᪵ឋḄ_ᡂ`a~஺(4)"Ḅ-./0ᨵᩩ6⁐-஺Ḅ`)./A)ḄᦪᑖCAe*+஺pᦪᑖC06⁐-JḄᐸ`a#஺43.᝞8ᵬ#DNAᑖᱏ\Ḅ᪀88:#DNAᑖᑴv8஺nᑡ⚪~(1)8ᵬ0⊤=M?᪶ᵞ⏚ḄᦪGᔠ#,᪶ᵞ⏚ḄVW#஺(2)8:0DNAᑖᑴḄ¡¢£#(¥¦)¨ᔠᡂḄ©ᩩ£(¥“mB”ᡈ“«⊡”)஺(3)DNAᑖᑴḄKL0ᐸᱯḄ᪀Jᑴ¯°±²³Ḅ¡¢´K`ᑣ¶ᜧLO·¸±ᑴḄ¹³ឋ஺(4)DNAᑴḄᱯºᨵ,ᑴKL0◤⌕Ḅ⏘ᨵo44.½¾jMV¿ÀÁÂÃÄḄᵱឋÆὅH-5,ᐸÈÉÊË᝞8ᡠ=mᐵÍaᵨAஹa⊤=஺ÎÏÐjÑ#MᓫÍa⍡{ÑÁH-1AÓÔÕÑÍa஺nᑡ⚪~(1)Ö8ᑨØÕÑÍa#ÙY6⁐-O(Úឋஹ◚ឋ)Ía஺(2)H-2ḄÍakJ,ÜH-2ÍakMÝmBḄÞᨵ?-஺H-1H-2)M?AÆÑßḄᭆ᳛J஺(3)áH-6?-Üᵱឋâr*+ÆÑḄᭆ᳛J«(4)´KäåæᶭèÂÃÄḄéêᨵëìJ´Käåæᶭ*ÂÃÄAíî⍡{ï*+nᑨØðñ#ᔲ³óðôᳮᵫ஺45.ÍaᢣøᔠᡂḄKLJᩖᨵᐵùú᝞8஺820Ḅᵞஹᜩஹ⁐ஹ;⊤=ᵞü⏚ஹᜩýü⏚ஹ⁐ü⏚;ü⏚ad⊤=./ᑁmᐵᱥᡈ᪀ÿ3
ᑣae
ᳮ஺ᑖ᪆8⚓ᐳ32⚓

8bMlM2N311ᨵ᪶!Ḅ#ᐰ#ᡂ&᪶'ᔠᡂḄᱥ*+,“./”ᡈ“2/”3ᑨ567஺+22ᡠ!Ḅ7,:Ḅ;ᡠ<=ᱥᑖ>7+ᵨ2Ḅ@A⊤!3஺CDEF⏚HIᨵJKṹMNCOPQRNDOPSᱥḄTUVḄWX7o31Y᪾ᑁᡠ!ᳮ
3Ḅ+ᵨ@A⊤!3\3cᡠ◤⏘Ḅ_`
஺46.abᔁdḄe⁐gSh⁐g
iឋkᑴ:.SឋmḄSnoFp+Aஹaor3s<8st⁐'஺u⊤7vᔠᔁdᩖxyzḄ{|ᦪ:Fi᪛F2᪛ᔠe⁐gh⁐ge⁐gh⁐gজe⁐gXh⁐g121045130ঝe⁐gXh⁐g89024281ᑖ᪆,ஹ+1ᔁdg⁐ឋmḄ⍡⍳_____ᳮᵫ7______஺2⊤ᔠজḄFp
ᳮ'ᔠজḄF2Iye⁐gvᔠMᡠᓰḄ
஺3⊤ᔠঝḄe⁐gḄFp
஺ᔠঝḄBh⁐gᔁdᩖxᳮ'&Ḅ⊤O
஺+4ᵨ+1⊤!.ᐵt⁐ᵨ+•3⊤!.ᐵFpo஺ᙠ᝞ᙊᙌ¡ᔠজḄR¢£ḄFp!W஺

9ᫀ<᪆1.ூᫀ௃Cூ᪆௃ABDஹᱥgᾙ¢£ஹ©Ὶ'«¢£<¬¢£®7¯°ᑖᓄḄ¢£2ᑖ²2ᐹᨵ¢£ᕜµABD┯·\Cஹ¸¹º¢£I»¼½¾¿ᨵÀᑖ²ᐹᨵ¢£ᕜµC┯·஺ᦑ⌱Co¢£ᕜµḄᭆÄ:¼½ᑖ²Ḅ¢£,ÅCÆᑖ²#ᡂÇÈÉᑮuCÆᑖ²#ᡂÇ
Ë஺⚪ὃ΢£ᕜµḄᭆÄWᙠὃÎÏSFẠÑÒḄᳮÓÔÕ°2ᜧ஺2.ூᫀ௃Bூ᪆௃AஹᑴᱏḄØ7“ÙCÚÛCt⁐Cᑴᱏ"A┯·\Bஹᑖ²µ¢£t⁐Ý᝱ßஹᦪàáᨎ7ãät⁐Ý᝱<ᦪàḄᨬæǵpçãäÇè✌ᐜë¡ᑖ²µ¢£ìë¡ᐸîǵ¢£Bïð\CஹᙠÙÇ¢£ñòᩔôᦑ2I⌱õC¢£ãäᑮᨵÀᑖ²ḄᐰC┯·\Dஹ¢£ö7÷µø¡OḄpçµãä2ᑮ¢£öD┯·஺ᦑ⌱Boãäᱥ¢£ᨵÀᑖ²ùz1ஹÙúõ᪷ü2-3mm+ᨬýþᜩḄ10-14
᪷℗᪷ᨵᑖᓽᐭᨵᑖᦪ15%Ḅᓄ!"#$%ᑖᦪ95%Ḅ⏀'!"Ḅ(ᔠ"*1+1Ḅ,ᴻ./ᙠ123453-5min஺2ஹ89+:᪷⏍<=ᵨ?@AᐭᨵBCḄ,ᴻ./89D10min«3ஹE⁐+G℗᪷HᨵIJ0.01g/mLᡈ0.02g/mLḄLMN!"ḄOP./E⁐3-5min஺4,ᑴᱏ+STUV,ᱏᙠ/WXSXBCYE⁐Ḅ᪷ᵨ╨@AᐭV,ᱏḄCX/[\ᵨ?@G᪷]^_`_,ᱏᙠ_,ᱏabSV,ᱏ.ᯠ=ᵨeᢣggᙢiV,ᱏ.3=b`V,ᱏᓽᑴᡂkᱏ஺5ஹlm+*1no?lmGᑴᡂḄ℗᪷kᱏᐜᙠno?3lm⌕rsᑮᑖuvḄwxᱯ
+wxᕈ{|}᣸ᑡᨵḄwx{ᙠᑖ஺*2o?lmsᑮᑖuvḄwx=Gno?ᣚ`o?ᵨwᯖ#ᐝ?G᦮ḄBᨎᑮBwxᱥ஺⚪ὃlmwxḄᨵᑖ¡⚪◤⌕ὃu£¤Ḅw⁚¦᝞¨©Ḅªᳮஹ¨©¬ᵨḄ|ஹ¨©®¯°±²¡⚪◤⌕ὃuᙠ³Ḅ´µ¶·/£¤%¸஺3.ூ»ᫀ௃C¾10⚓ᐳ32⚓

10ூ4᪆௃4+Aஹ¦wxuᱥ☠wxÄÅᩭÄbwxḄᦪǶwxᑖᓄᩭÄbwxḄÈA┯ÊËBஹª᪶wxḄᑖ|ÎÏᑖÐᑖÑ᪶wxḄᑖ|ÎÒSB┯ÊËCஹᓫwxuᱥ$ǶwxÄÅÕÖ×C{ØËDஹwxÄÅᒹÛᱥᜓ#wxᑖÝÞßàḄ¶·D┯Ê஺ᦑ⌱+Co1ஹÑ᪶wxḄÄÅ|ÎᒹÛᨵᑖஹÐᑖ#åᦪᑖᐸ/ᨵᑖç⌕ḄÄÅ|Î஺2ஹª᪶wxḄÄÅ|ÎÏᑖ஺⚪ὃwxÄÅḄéᐵëì⌕rὃuìíª᪶wx#Ñ᪶wxḄÄÅ|ÎîØwxÄÅḄ¤ïðñᔠᡠ´ḄëìØ»⚪஺4.ூ»ᫀ௃Dூ4᪆௃4+wxᐰðឋḄöẠøÞ$wxùúᨵûᱥÈᡠᱯᨵḄᐰᝅ⍡þᱥùᨵÿᡂ᦮Ḅᐰ஺᪷ᓫ᜜ᡂ᦮Ḅ஺ᐸ᪷᪷ᐹᨵ#ᱥ%Ḅᐰᝅ஺ᦑ⌱)D஺ᐵ,Ḅ“ᐰឋ”0121345☢78)91;ᭆ=)Ḅᐰឋᢣ?ᑖᓄḄBᯠᐹᨵᑖᓄDᡂE%Fᡂ᦮ḄGḄᱯឋ.92;ᐹᨵᐰឋḄ)Kᨵ#LᱥᐰḄ⍡NᱥO.93;ᐰឋᜧR)STᓿVWVLXV.94;⊤[\ᐰឋḄᩩ^)_ஹ〉bḄ⃩ᩩ^ஹ〉bḄd᛻ᩩ^.⚪ὃhᱥijḄkᐵlmnᙠὃhpLḄmqrFᑨtru,vᓫ⚪஺5.ூyᫀ௃Dூ|᪆௃|)Aஹ⊦ὁᑁᑖᔾ᠒ABஹ⊦ὁᑁᨵ⏘ḄឋBCஹ⊦ὁ⁐⌲CDஹ⊦ὁRD┯஺ᦑ⌱)D஺⊦ὁḄᱯ)91;ᑁᑖ¡R¢᪶¤ᜧ¥⁐O¦¡¥⁐§¨92;©ª«ឋ¬ᦋᱥO®¯¬93;⁐°Ḽ⊦ὁ⌲94;ᨵ⏘Ḅឋ95;ᔾ᠒²▰´µ᠒.⚪lm¶vᓫὃh⊦ὁḄ·⌕ᱯ¹⌕ὃLmq⊦ὁḄ·⌕ᱯᓽ0

11y⚪u,ὃ¼mq½¾Ḅὃh.6.ூyᫀ௃Cூ|᪆௃|)Lᱥᑁ¿ÀÁÂ¥ḄḄÃ◀ÅÆᨵᑭÈÉᡂḄ஺ᦑ⌱)CoᵫᡠÌÍḄÎÏÐÑLÒḄÓÔÕÖÈÉ஺ᵫ,ÈÉSᑮØÙḄᵫ⍡NᱥOÌÍḄÔÚឋÛÜᡠ1ÝÞÞ¿ßàÔឋáÉ஺ᙠᡂâḄLᱥãḄÎᯠ䲿ÀÂ¥ḄḄÃ◀ݪÓÈÉᡂḄ஺ÈÉÅ,åæ᜜çᔜ%ḄW᡾êëḼìÞᐵíḄîᵨ஺⚪·⌕ὃhÈÉḄᑁð⌕ñὃLmqkᐵlmòÐᔠᡠplmôy⚪஺7.ூyᫀ௃Bூ|᪆௃|)AஹTtõÅö÷ᡠ1u,ᩖᔠùA┯BஹccDDeeúÅêûᔠḄûᔠùBCஹAaffõÅᩖᔠõÅûᔠḄᩖᔠùC┯DஹGGXBXbõÅûᔠõÅᩖᔠḄᩖᔠùD┯஺ᦑ⌱)B஺ûᔠüßýþᔠùᡈ
ᔠ஺ᵫḄᡠᔠᡂḄᔠᢣᵫᔠᡂḄᱥ஺ᔠḄ⁐ᙠᐸ"#Ḅ$"ᡈ&"'()*ᙠḼ,ᐰḄ.(᝞AAஹaaஹAABBஹAAbbஹaaBBஹAABBcc.aaBBcc..ᐹᨵ34Ḅᱥ534ᡂ"Ḅᩭ789ᔠ஺ᙠ:;Ḅ<=>?@3&"ᡠAᑴḄឋDEFᑖH஺ᓽᙠ@J$"89ᔠḄ஺K⚪M⌕ὃPឋDḄQஹ◚ឋᐵTUஹ⊤WᐵXYZᑭᵨᔠḄᭆ^_⚪஺8.ூcᫀ௃Dூ_᪆௃_gAஹhiḄᙊklmḄnoᔠ“ᱥ”rEoᔠ“$ឋD”Est"ឋDA┯vwBஹxmḄyzl{zoᔠ“ᱥ”rEoᔠ“$ឋD”Est"ឋDB┯vwCஹᐢḄᮞ~lḄ~oᔠ“$ឋD”rEoᔠ“ᱥ”Est"ឋDC┯vwDஹ∫Ḅloᔠ“ᱥ”“$ឋD”st"ឋDD஺ᦑ⌱gD஺"ឋD9ᢣᱥឋDḄE⊤W஺ᑨᱥḄឋD9ᔲst"ឋD,◤⌕ᡷᐵ“ᱥ”“$ឋD”c⚪஺K⚪ὃPᱥḄឋDl"ឋDZὃP"ឋD⌕ὃY"ឋDḄᭆ^12⚓ᐳ32⚓

12ᡷᭆ^@Ḅᐵ“ᱥ”“$ឋD”"ᔜ⌱⚗ḄᑨstὃYᳮ_¢£ḄὃP஺9.ூcᫀ௃Aூ_᪆௃_g¦1¨ᵫtᜧi9ªmᣴ¬Ḅᱥ<=ᨬ¯°ᜧiḄ±m"m²Qឋᡠ³⌕␺µ$¶±mᜧiḄ◤⌕·¸±mᜧi<=¹>?ºឋDᑖHᑣ²ᔠw¹>?ᨵឋDᑖHᑣ²ᩖᔠ஺¦2¨ᵫt¾¿9ÀÁÂÃᱥ¾¿ḄÄÅ"ÆÅ9Qឋᡠ³⌕␺µ$ÇÄž¿Ḅ#ÈÄž¿lÉÇ◚ឋ=ᓽÊ=¹>?ᐰ²ÄÅᑣË̲9ᔠw¹>?ᨵ◚ឋWᑣ9ᩖᔠ஺ᦑ⌱gAo␺ÎÏÐg¦1¨␺Î$ÇÃᱥ9ᔲ²ᔠËᵨÊ=Ðw¦2¨␺Î$Ñᱥ9ᔲ²ᔠËᵨÊ=Ð<=Ðᐸ@<=Ðᨬ¯°w¦3¨␺Î$""ឋDḄQឋ◚ឋËᵨᩖ=Ð<=ЦÇᵨtᱥ¨w¦4¨ÔÕÖ×ØḄÙÚᵨ<=Ðw¦5¨ÜÝᩖBḄßᵨÊ=Ð஺K⚪ὃPᑖHµàḄá
U#ᵨ⌕ὃâãᑖHµàḄá
äFåᵨEḄÏÐæç␺Îᡷ⚪è@ᐵ“ᨬ¯°”⌱Ḅcᫀstὃᳮ_¢£ḄὃP஺10.ூcᫀ௃Dூ_᪆௃_gAஹhi9

13⚪ὃrst⍡C⌕ὃ¡@AḄᱯ£¤¥rst⍡CuJᡂKḄL¦3ᔠᡠDḄ¨©ᑨ«ᔜ⌱⚗஺11.ூ°ᫀ௃Aூ´᪆௃´=Aஹ)¶ឋXᑖ·3=1¸¹ឋec◚ឋ»ᐰ¹ឋ½᝞¿¹ឋ]ᔠ)ᩖᔠ)⊤ÁḄឋX.Âᑣ)¶.Äᔠ3=1ឋXᑖ·ABஹÆ)[/0ឋÇÈ·ÉeÊḄË^()ᑣ)¶ឋXᑖ·3=1,B┯9CஹÆ)[ÈḄ0(),2^ÍÎ()ÏÐÑÒÓ/()ÔÑÒÓᑣ)¶ឋXᑖ·3=1,C┯9DஹƸ)¶3^Î{ÕḄÖÏ᳛eÊᑣ⊤ÁηÉ3=1,D┯9஺ᦑ⌱=A01ஹÙᑴ.ÂឋXḄ⍡C)ḄᑖᔠÛ.Ü᡾Ḅᙠ&ᡂ()¸ÞÂ[ឋXḄᡂḄ⍡C)ß½ᑖÞ.ÂឋXḄ⍡C)ᵫᔠ஺2ஹᙠᱥÕḄÕàá,ÙᑴÂ[^ឋXḄ⍡C)ᡂÖᙠ.eâᔠᙠ&ᡂ()¸ᡂḄ⍡C)ᑖᑖ~Ḅ⍡C)ᑖã
ᐭ.ÂḄ(),1()⍡Cå~஺⚪ὃDæ⚪Ü,uIeᐵèéê3ᔠᡠDrstᑖḄ¨ëᑨ«,ìc¡ᳮ´îïḄᑁGñò〉,஺12.ூ°ᫀ௃Aூ´᪆௃´=AaBbAaBBË^ÎḄ@A{Õᩖöᵨ⌲ᑖ᪆ø஺AaxAa-1AAஹ2Aaஹlaa,BbxBB-IBbஹ1BB஺½)[ḄÎ^Í3x2=6^¦ÿ⍡Ḅᔠᡠᓰ=224ᦑ⌱A஺⚪ᨬᓫḄ⌲!ᑖ᪆$ᓽ✌ᐜ()ᵫ+ᔠ,-⚪.ᓄ01ᑖ2,-⚪3ᐸ5᪷789Ḅᑖ2,:;<=>!?!ឋAᡠBḄ$ᨬCD?E஺⚪ὃG89)ᵫ+ᔠ,ḄHIJKᵨ$⌕BὃNOP89)ᵫ+ᔠ,ḄHI$QRSTᵨ⌲!ᑖ᪆:;?ᐵᭆ᳛$XYὃZᳮ\5ḄὃG஺13.ூᫀ௃Cூ᪆௃Aஹ$yyx6yyTCijklmno⁐$9qrQsiḄ⊤uvᑨx<ឋy$A┯{3Bஹ$~yxdyy-Cimឋᨵ⁐ᨵo⁐$lឋno⁐$ᡠrQᑨxo⁐CiḄឋy$B┯{3Cஹyy*dYY-CiCimឋn⁐$lឋno⁐$siḄ⊤uv14⚓$ᐳ32⚓

14ᑨx<ឋy$C3DஹYy*6Yy-Cimឋᨵ⁐ᨵo⁐$lឋno⁐$ᡠrQᑨxo⁐CiḄឋy$D┯{஺ᦑ⌱CoY⁐yo⁐Y≆≈⁐Ḅ>!89$mឋᨵ⁐o⁐$lឋᨵo⁐$ᓽmឋ≆≈$89v~>⊤u⁐ឋA$89vyyḄ⊤uo⁐ឋA$lឋ≆≈jk89vn⊤uo⁐஺⚪ὃG89ᑖ2,ḄHIJKᵨ$⌕BὃNOP89ᑖ2,ḄHI஺⚪Ḅᐵ¡ᡷ£⚪1¤¥“mឋᨵ⁐o⁐$lឋᨵo⁐”ᑨx=⌱⚗Cir©ឋyḄ⊤uv$D⌱<Ḅ⌱⚗$XYὃZᳮKᵨ\5ḄὃG஺14.ூᫀ௃Bூ᪆௃AஹttSsxTTSsḄCin®T,ᡠCiK°±²°³²=31,A┯{3BஹTtSsxTtssḄCi°±²°³²o°±²o°³²=331LB3CஹTtSsxTtSsḄCi°±²°³²o°±²o°³²=9331,C┯{3DஹTtSsxttssḄCi°±²°³²o°±²o°³²=1111,D┯{஺ᦑ⌱Bo᪷7⚪¶ᑖ᪆·°T±²S᳝¹º᳝¹ᩖ¼$Ci⊤uv᳝¹Ḅ89vTtss.⚪ὃG89)ᵫ+ᔠ,Ḅ?ᐵ·Æ$¶ᙠὃGÈNḄÆÉQÊᑨxQÊ$TᵨᡠÈ·ÆËᔠᑖ᪆-⚪Ì-⚪ḄQÊ஺15.ூᫀ௃Bூ᪆௃AஹCCxccḄCi89vCc,CiÏᑖÄÏÐ⁐Ñ$ÒᨵÓÑ

15Ñ$cc⊤uoÑ$Cc⊤ußàvḄá⁐Ð⁐Ñ஺⚪ὃG89Ḅᑖ2,ḄHIJᐸKᵨ?ᐵ·Æ$¶ᙠὃGÈN!âÈ·ÆḄᳮãäஹᑖ᪆-⚪ஹÌ-⚪ḄQÊ஺16.ூᫀ௃Dூ᪆௃Aஹ᪷789)ᵫ+ᔠ,$åᩖᔠḄB)¼æF2,F2ᨵ989v$4⊤uv$A3BஹF2ç!ឋAᑖèᑖ᪆$=>!néᔠ89Ḅᑖ2,$ᡠêëìºíîìÄ31,ï⁐ºo⁐Ä31,B3CஹF2ºÀ⊤uv?©Ḅᜧñᓰæ+æ=*,9q᫜ᑁḄDdᔜüý10$Å>᫜ᦪÿ
ḄᦪᓿḄᨵḄA┯Bஹᵨ!"#$%&'(#$)ᔠᙳᒴ-%./!"#$ᦋᣚᩞ3ஹᜧ567Ḅ5ᳫ.9ᐙᑖ)ᔠ<=>?B@ACஹ᝞CDᢕFGHᨵIᢕFḄJᩈLM᫜OC(PQᢕFḄᭆ᳛6Tᡠ.CDᢕFGVIᢕFḄ#$LM᫜WXC(#$QᢕFḄᭆ᳛6T,C@ADஹᢕGLM᫜᤯ᒴWX[Ḅ\]ᑖP^PḄ\]ᔠ_`50100DWX᪵bᦪcdᜧ.ef?D@A஺ᦑ⌱jAoklDDDdddTm121,noᔠ@pḄ஺ᜫrḄjCDᢕFGHᨵIᢕFḄ!"#$LM᫜C(PQᢕFḄᭆ᳛6T஺b⚪ὃuឋwᑖx#yzm-{|⚪◤⌕ὃḄ⁚᝞ḄᳮஹᵨḄ!ஹT◤⌕ὃᙠḄJ஺16⚓ᐳ32⚓

1618.ூᫀ௃Bூ᪆௃jAஹ¡ᑖ"ᒹ£2ᩩ¥⁐"ᓽ£ᨵ'Ḽ©ªA┯Bஹ¡ᑖ"ᒹ£4ᩩ¥⁐ᓫ"ᓽ£4¬DNAᑖB@ACஹ¡ᑖ"ᒹ£ὶOGCz7¯¥⁐"Ḅ4ᩩ¥⁐ᓫ"C┯Dஹ¡ᑖ"ᒹ£z7¯¥⁐"D┯஺ᦑ⌱jB«¡ᑖ"ᢣeᦪDᑖ±7¯¥⁐"ὶOGCz7¯¥⁐"£ᨵ¡ᩩ¥⁐ᓫ"஺¡ᑖ"=z7¯¥⁐"=2ᩩ¥⁐"=4ᩩ¥⁐ᓫ"=4DNAᑖ஺b⚪ὃuḄeᦪᑖ±_ªὃu¡ᑖ"Ḅ6ᐵ´µ⌕¶ὃµ·¡ᑖ"Ḅᭆ¸¹º¡ᑖ"Ḅᦪᐵ»¼ᔠᡠḄ´µ½Aᑨ¿ᔜ⌱⚗஺19.ூᫀ௃Dூ᪆௃jAஹÂÃÄÅ£ᨵ1ᩩÆ¥⁐"A┯Bஹᜐmᨵ©ᑖ±ÈÉḄÅ£ᨵ1ᩩÆ¥⁐"B┯CஹᜐmeᦪÊDᑖ±ÈÉஹÉḄDÃÄ%&£ᨵ1ᩩÆ¥⁐"Ë%&£Æ¥⁐"ᜐmeᦪÊDᑖ±GÉḄDÃÄ%&£ᨵ2ᩩÆ¥⁐"Ë%&£Æ¥⁐"C┯Dஹᜐmᨵ©ᑖ±GÉḄᵫmḼ©ªᑖ±¥⁐"ᦪÍÎÏᡠ.-ÉÐÑ£ᨵ2ᩩÆ¥⁐"D@A஺ᦑ⌱jD஺eᦪDᑖ±ÒÉḄஹeᦪDᑖ±ḄÂÃÄஹᨵ©ᑖ±ÒÉஹÈÉஹÉ^ÓÉḄÔÅ£ᨵ1Æ¥⁐"eᦪÊDᑖ±ÈÉ^ÉḄDÃÄ£ᨵ1Æ¥⁐"ᡈ£Æ¥⁐"eᦪÊDᑖ±GÉḄDÃÄ£ᨵ2Æ¥⁐"ᡈ£Æ¥⁐"ᨵ©ᑖ±GÉḄ£ᨵ2Æ¥⁐".b⚪ὃuᨵ©ᑖ±^eᦪᑖ±Ḅ6ᐵ´µ_ªὃuᨵ©ᑖ±^eᦪᑖ±¥⁐"Ö
ᓄ^ᦪÍ
ᓄØÙ⌕¶ὃµ·ᨵ©ᑖ±^eᦪᑖ±7ÉḄᱯª&½Aᑨ¿ÛឋÜᱥᙠ7ᑖ±Éᡠ£ḄÆ¥⁐"ḄᦪÍ஺20.ூᫀ௃Bூ᪆௃jAஹÞßàᵨkl!ᑖ᪆áâ⍡äØÙÞßà⍡äåæᡂèḄéA@ABஹêë^ìíì.DNAîïðñḄ6ᐵᦪò[ẠôõöDNAᑖᕈøù᪀B┯Cஹ⃬üᵨ{ᳮI[ý¥⁐"þÖ{ÿ“ᙠ⁐”ḄᎷCDஹ᥅᪷ឋឋḄᐵὶᵨᎷ!"#$ᙠ⁐D஺ᦑ⌱(Bo

171ஹ*+,-⍡/01ᵨ2Ꮇ!"ᐸ456(78⚪:Ꮇ!;ᳮ=>>#?@A=>BCDE஺2ஹ⃬GHᵨIJ;ᳮḄK"7ᙠ⁐ḄᎷ᥅᪷HᵨᎷ!"#$ᙠ⁐஺4⚪ὃMNIO⍡/ᱥQḄRSᔊUOVIW⚪◤⌕ὃZ[\Ḅ]⁚_`᝞=>Ḅbᳮஹ=>ᵨḄK"ஹ=>-cdDE◤⌕ὃZᙠefḄghiUj[\kl஺21.ூoᫀ௃Bூr᪆௃r(Aஹt∫Ḅv⌕w⁐V᜜ᙠyzj{ᨵ}~ḄA┯Bஹᩋᙠ]jᙠ4᝞ᩋᔠḄ]ᙠᨵᑖfᨵ4ᩋBCஹjᩋwᩩ⁐wC┯Dஹᩋwᩩ⁐VZ]jfᙠᩋD┯஺ᦑ⌱(B«ᑖ᪆⚪(t∫ᩩ⁐Ḅwᩩ⁐ᙳw஺4⚪DᔠrὃMḄᐵ¡¢⌕£ὃZ¢¤Ḅᭆ¦§¨DNAஹ⁐Ḅᐵ©ᑖ᪆⚪ªDᔠᡠg¡¢¬ᑨ®ᔜ⌱⚗.22.ூoᫀ௃Cூr᪆௃r(Aஹ±²³ᓄ³ᓽ¶⁐◚ឋ⍡/³ᑣHI-9Ḅ¹aa,ᑣII-8ºH-7Ḅ¹»Aa,H-5Ḅ¹aa,ᑣI-1ºI-2Ḅ¹»Aa,ᑣII-6Ḅ¹¼aᡈ!AA,VII-6II-7Ḅ¹Ḅᭆ᳛3#A333Bஹ±²³À⁐ÁᓽÂX⁐◚ឋ⍡/³ᑣIH-9Ḅ¹X'Y,ᑣIH-9ḄóᩭÅᐸÆÇH-7?¹XAXD,II-7Ḅ᱄ÇI-1⊤-¶?¹XAY,VH-7ḄóᩭÅᐸÆÇ1-2,ᦑIII-9ḄóᩭÅ1-2,B;CஹᢙÌZÍDÎϳÂX⁐Ðឋ⍡/³±²³ᢙÌZÍDÎϳᑣH-7Ḅ¹xaxa,II-8Ḅ¹XaY,ᑣH-7ºH-8ḄÑ»¶‘ÓZÔ³ḄW-9,$²³ÓᢙÌZÍDÎϳC┯Dஹ±1-1ஹ1-3ºH-8{Ô³ᓽÔ³Ḅ»ᵱឋᑣ²³ÂÖ⁐⍡/³D஺ᦑ⌱(Co×18⚓ᐳ32⚓

18᪷Ú⚪ᦻº©Üᑖ᪆(ÝÞjᵫOw?àA/aBäᑴḄ⍡/³Ḅ⍡/©ÜᐸjI-1ºI-2ᙳ¶Z2Ô³ḄII-5,$²⍡/³◚ឋ⍡/஺4⚪Dᔠ©ÜὃM¶ìḄNI⍡/³⌕£ὃZ¢¤í¶ìḄᓫ⍡/³dᐸᱯð᪷Ú©Üd⚪à;®ᐸ⍡/KñᯠªDᔠ²⍡/³Ḅᱯðo⚪.23.ூoᫀ௃Cூr᪆௃ூᑖ᪆௃4⚪ὃMᑖõ01Ḅ=QdöᵨஹÂឋ⍡/⌕£ὃZ§¨ᑖõ01Ḅ=QºÂឋ⍡/Ḅᱯð᪷ÚÇ4Ḅ¹¬;®BḄ¹øù;®F2jûüýºûüýḄJþ஺1ஹÂឋ⍡/ᢣᙠ⍡Ḅᑖឋᵫឋ⁐Ḅᑴᵫឋ⁐ḄᡠᑴឋḄ⍡ឋ⍡஺2ஹᑖ#$%Ḅ&'(ᙠᩖᔠḄ+,-./012⁐Ḅ3-ᐹᨵ/$Ḅ67ឋ89ᱥᙠ;<=ᦪᑖ?@ᡂBC3-DEḼ12⁐ḄᑖGHᑖ#ᑖI;ᐭᑮLMB67ᙢEB⍡OP஺ூRS௃UVWXYZBZB\]^VWXYZbW\aBb9F”FiḄLgYZBZbxZBW\aBiᑮF2,F2Ḅgஹ⊤lgmnoZBZBYVWX\(ZBZbYVWX\(ZBWYVWX\(ZbWY^VWX\=1(1(1(1.sF2VWX]^VWXḄnot3(1,ᐸwឋMVWXx^VWXḄnot1(1஺ᦑ⌱C஺24.ூSᫀ௃CூR᪆௃R(Aஹᵫ.ᵱឋḄX⁐⌴O᝕sX⁐ឋ⍡ḄᵱឋὅḄ᝕tὅA8Bஹ᝕ὅ.ᵱὅtXឋ⍡Ḅᱯ/B8Cஹ◞⍡t◚ឋ⍡Ḅᱯឋ⍡/ᐹᨵ⍡ḄᱯC┯8Dஹᵫ.ᵱឋḄX⁐ᩭsX⁐ឋ⍡ḄᵱឋὅḄ/$D஺ᦑ⌱(Co1ஹX◚ឋ⍡Ḅᱯtᵱὅ.᝕ὅ,ᵱὅḄᵫ᝕⌴O᜜᝕ὅḄ᱄]tὅ஺2,Xឋ⍡Ḅᱯt᝕ὅ.ᵱὅᵱὅḄ᝕]tὅ᝞᝕ឋ¡᱄]¡஺¢⚪ὃ¥ឋ⍡Ḅ¦ᐵ¨©⌕«ὃ9©¬ឋ⍡Ḅgmᱯ®ᐸtX⁐ឋ⍡Ḅᱯ¯°ᔠᡠ±Ḅ¨©²S⚪஺

1925.ூSᫀ௃DூR᪆௃R(Aஹ³¯1Cᵨµᨵ32P]35sḄ¶·¸ᜧºᩚ·ᔲᑣ¾¿ᑨÁÂÃឋḄᩭ2A┯8BஹÄ&ÅÆÇȶ·Ḅ⍡ᱥ'tDNA,B┯8CஹᤅÊtÈËᔾ▬ᙠᜧºᩚ·ḄÎÏ'᜜Ðxᜧºᩚ·ᑖGC┯8Dஹ#ÑtÈÒÓÔÕÖḄᜧºᩚ·˶·ḄÎÏ'᜜Ðᑖ×ᑮØÖD஺ᦑ⌱(D஺1ஹ¶·Ḅ°᪀(ÎÏ'᜜ÐYCஹHஹ0ஹNஹS+DNA
CஹHஹ0ஹNஹP஺2ஹ¶·ḄÚÛ(ᔾ▬/ÜᐭYÜᐭ¶·ḄDNA/ᔠᡂYᑴὅ(¶·ḄDNA8Ýᧇ(+·Ḅᓄ±ᡂᑖ\/àá/âÂ஺3ஹT2¶·¸+·Ḅ&Åãä(ᑖIᵨ35sᡈ32P᪗¬¶·/¶·xᜧºᩚ·çᔠÔÕ/¶·¸èé᪗¬Ḅ+·/ᙠᤅÊᘤᤅÊᯠP#ÑìíØÖ]ÒÓᱥḄÂÃឋᱥ'஺¢⚪ὃ¥¶·¸+·&Å0.sî⚪◤⌕ὃ9ÜðḄ+⁚ò᝞&ÅḄÝᳮஹ&ÅôᵨḄ¿ஹ&Ålõm°ö3◤ὃ9ᙠ÷CḄ±øÜðùú஺26.ூSᫀ௃DூR᪆௃R(ABCஹSg+·ḄÎÏ']û³tüᓄ³¯ýRg+·üᓄSg+·s³Db9ᐝÿ
ABC┯DஹSḄDNAᓄRᓄSᐝḄ
D஺ᦑ⌱D஺1ஹᳫSR
ᐝ"#$ᨵ&'()*+&'()*,ឋᨵ,ឋ./012⊈456+,ឋ720⚓ᐳ32⚓

202ஹ<=>?@DNA⍡EᱥGḄHIJᳫ$᜜ᓄHILRTḄḄMN4•ROPḄM*&S⚪ὃVᳫᓄHIWX(Y⚪◤⌕ὃ\]Ḅ⁚_&᝞HIḄaᳮஹHIcᵨḄefஹHIghijkl◤⌕ὃᙠnoḄpqrst\]uv஺27.ூzᫀ௃Dூ}᪆௃}ᵫDNAᑖt⊡WaᑣDNAᑖt⊡WḄᓰᦪḄᓽA+Gᓰ50%,AḄᦪᓰ30%,ᑣJGLḄᦪᓰ20%,JGLḄᦪ150x2x20%=60£஺ᦑ⌱D஺⊡WaᑣᙠDNAᑖt⊡¤¤¥lA=T,C=G,A+G=C+T,ᓽ¨ᦪlXᗌªᦪ஺S⚪ὃVDNAᑖj᪀Ḅ¬⌕ᱯ®⌕¯ὃ°±DNAᑖj᪀Ḅ¬⌕ᱯ®²³⊡Waᑣiᐸµᵨ¶ᵨᐸ·¸¹º»z⚪¼Xὃ½ᳮ}µᵨ¾¿ḄὃV஺28.ூzᫀ௃Cூ}᪆௃}AஹWᦪ&ÁÂÃ᪶⏚ᑖḄj᪀ÂÃᐸÆÂÃWḄᦪÇÈ᪶⏚ᑖ&᪵ឋᨵᐵABஹ᪶᧖⏚Ḅ᣸ᑡÏÐÂÃ᪶⏚ᑖḄj᪀ÂÃÆÑÂ¥Ã᪶ᵞ⏚Ḅ᣸ᑡÏÐÈᑖ&᪵ឋᨵᐵBCஹ᪶ᵞ⏚È᪶ᵞ⏚ÓÔrÕ⏚Ö×ØÙÚDNAḄWÓÔrÛØÙÚÂÃᑖḄ᪶⏚᪶ᵞ⏚ḄÙÚeÜ¥ÃÈ᪶⏚ᑖj᪀&᪵ឋ+ᐵC┯Dஹ᪶ᵞ⏚ᦪ&ÁÂÃ᪶⏚ᑖḄj᪀ÂÃᐸÆÂÃ᪶ᵞ⏚ḄᦪÈ᪶

21⏚ᑖ&᪵ឋᨵᐵD.ᦑ⌱C.᪶⏚ᑖj᪀Ḅ&᪵ឋᵫ᪶ᵞ⏚ḄÝ(ஹᦪ᣸ᑡÏÐÞßḄ᪶ᵞ⏚Ḅ᣸ᑡÏÐⅾáḼ⍡Eãä᪶⏚ᑖj᪀Ḅ&᪵ឋÞßÆḄ&᪵ឋ.S⚪ὃV᪶⏚ᑖj᪀i&᪵ឋḄa᪶⏚ᑖj᪀&᪵ឋÈÆ&᪵ឋḄᐵåWX᪶⏚j᪀ÈÆ&᪵ឋḄᳮ}}⚪ḄᐵØ}᪆o⌕æᡂj᪀ÈÆ¥〉µḄᱥpé®.29.ூzᫀ௃Bூ}᪆௃}Aஹজ⊤ìDNAíᑴḄrsA┯BஹঝðrsᨵAÈUWBCஹঞòórs◤⌕tRNAôÈটRNAḄöᡃíᑴÂ◤⌕tRNAôÈC┯DஹT2ø$DNAù,ᐸúûrstÂüঠ⌮ðrsD┯஺ᦑ⌱B»ᑖ᪆⚪ÿ
জDNAᑖḄᑴঝঞটRNAᑖᑴঠ⌮஺⚪ᔠ
ὃᑣ!ᐸ#$⌕&ὃ'()ᑣḄ*⌕ᑁ,!-./ᐸ01Ḅ⊡ᐙ45ᗐ789ᑖ᪆⚪
;ᔠᡠ=Ḅ>(?9@⚪஺30.ூ@ᫀ௃Bூ᪆௃জ.DḄ⍡FᱥHIDNAᑖJKDNAᑖLMḼ⍡FOPজ89Qঝ⍡FRṹᙠmRNAUঝ┯WQঞIXDNAᑖḄYᩩ[\]ᔠᡂRNAḄJKDNA7mRNA,ঞ89QটmRNA70ᐭ᪶abcdḄ\]eDNAf70ᐭ᪶abট┯WQঠtRNA7ghij⏚eDNAf7ghij⏚ঠ┯WQডDNA7lᑴmnHḄᔠᡂড89஺ᦑ⌱Bo.bᑁḄ᪶⏚DrᒹtDNAஹmRNAஹtRNAஹrRNAvw1DNAḄx7LMḼ⍡FOPlᑴmnHḄᔠᡂQ2mRNAḄx7F⌴⍡FOPdḄ\]Q3tRNAḄx7(zRṹcg{|Ḅij⏚Q4rRNAḄx7}ᡂ᪶abḄ~⌕ᡂᑖ.⚪ὃ᪶⏚ḄwD!dᵨ⌕&ὃ'()᪶⏚ḄwDf᪶⏚Ḅdᵨ7᪷22⚓ᐳ32⚓

22⚪⌕&d?9Ḅᑨὃ()Ḅὃ.31.ூ@ᫀ௃Cூ᪆௃:জ
X⊤ᡈ⌮ef7⊤DNAᑴজ┯WQঝ
⊤DNAᡈ⌮ঝ89Qঞ
ᐳᨵ5wjᓽAஹCஹGஹT4U,ঞ89Qট
ᐳᨵ8w᪶ᵞ⏚vwῃ᪶ᵞ⏚4vw᪶᪶ᵞ⏚ট89Qঠ
ᐳᨵ8w᪶ᵞ⏚ঠ┯WQড
A⊤¡w᪶ᵞ⏚ᓽ¢£ἠ¥ῃ᪶ᵞ⏚4¢¦¥᪶a᪶ᵞ⏚ড┯W஺ᦑ⌱Coᑖ᪆⚪

§ᨵDNA4RNA¡ᩩ[§ᨵ5wjஹ8w᪶ᵞ⏚஺¨XDNA[\]ᑣ
⊤¨XRNA[\]ᑣ
⊤⌮஺⚪ᔠ
ὃ⍡FOP4ஹDNAᑖḄjᓫªஹRNAᑖḄjᓫª⌕&ὃ'()⍡FOP4Ḅ()DNA4RNAᑖḄj}ᡂᓫª789ᑨᔜ⌱⚗ὃ()Ḅὃ஺32.ூ@ᫀ௃Aூ᪆௃Aஹ'ᱥbḄឋ®*⌕IᵫjJ°±Ḅ²᜜´µ᛻·¸A89QBஹjJ¹ឋ®º»fI¼ᓫḄYY/|Ḅᐵ¾ᨵ¿ឋ®7ᵫÀ/jJlᑴᨵ¿jJÁ7·¸ÀwîC┯WQDஹjJ/ឋ®Ḅlᑴ⌶ÅIjJÆlᑴ⏘Ḅᔠᡂlᑴ'ᱥḄÈÉ0Ê»Ëlᑴ'ᱥḄឋ®ÌXÆlᑴmnHḄ᪀ÎËlᑴ'ᱥḄឋ®C┯WQDஹjJḄjÏᑡ{ÑjJ°±Ḅឋ®fY±{²᜜´µ᛻·¸D┯W஺ᦑ⌱Ao1ஹjJIᨵ⍡Fᦔ|ḄDNAᱏÔ,Ilᑴ'ᱥឋ®Ḅ⍡FᱥHḄx7ᓫª4᪀ᓫª,DNA4jJḄj}ᡂᓫªÖIῃ᪶ᵞ⏚஺jJᜧÀᙠØ⁐bUÚYᩩØ⁐b§ᨵÀÛjJjJᙠØ⁐bUᕈÝឋ᣸ᑡ஺2,jJ/ឋ®ḄlᑴßàজjJÆlᑴ⏘Ḅᔠᡂᩭ·¸âãÈÉ0Ê»Ëlᑴ'ᱥḄឋ®᝞nᓄæஹçèḄéÃ;ঝjJÆlᑴmnHᑖ᪀ᩭÎËlᑴឋ®᝞╢ᑐÃâãí⊈ïஹðឋñòæ஺⚪*⌕ὃᨵᐵó᪶'ᱥjJḄ>(⌕&ὃ'()jJஹDNA4Ø⁐bôὅº»Ḅ{öᐵ¾()µ᛻·¸jJḄ⊤÷()jJ/ឋ®Ḅlᑴßà7ᔠᡠ=Ḅ>(?9ᑨᔜøùὃ()4ᳮḄὃ஺33.ூ@ᫀ௃Bூ᪆௃AஹjJ~}#'ᙠᨵឋ'û'ᱥ01üᦪᑖþḄÊᝍ
ᦪᑖA┯

23Bஹᝍ
RNAᐸᩭBCDஹᝍ
RNA!⁐#$%&!⁐#'᪀)ᦪ*CD┯஺ᦑ⌱.B,/⍡1Ḅᨵ4ᩭ.ஹ!⁐#)56஺1'᪀Ḅᦋᒹ9:;Ḅ<=ஹ>ᜫᡈAᣚ஺%&ḄCDE⌕GHᑖḄDI஺ḄᱯKL⚣ឋஹOPឋஹQᑭSTឋஹUVឋஹWᔣឋ஺256ḄYZᨵ[!⁐#\]^_ᓫ#aDḄbcdᣚ)][!⁐#\]efaDḄgᵫ6ᔠj᜜᜜Ḅlᐭnopq56஺3!⁐#ᢣ!⁐#'᪀)ᦪ*Ḅᦋ஺!⁐#'᪀ḄE⌕ᨵ>ᜫஹ5sஹ᎔fஹ᧕fvwx஺!⁐#ᦪ*/yᑖz{w.wGHᑁ}~!⁐#Ḅ<ᡈQjwGHᑁ!⁐#ᦪ*y!⁐#6ḄZᡂᙢ<ᡈQ஺⚪ὃ&ᱥḄᩭᙠὃ&Ḅ$)ᑨ$ᜧ஺34.ூᫀ௃Aூ᪆௃.AஹGH&ឋ⊈%Ḅ᪷¢SLC5242£ᢝ¥ᵨ§&¨B2,/■ª«Ḅs%ABஹ¥ᵨ§&¨B2,z¬ὅ⊡ᐙ°§&¨ᩭ±²³sSLC52A2B┯Cஹ«ᙠᐰµ¶·¸¹{º»¼½¾#GH%&ḄᐹᨵL⚣ឋC┯DஹᑭᵨDNAᑖÀḄᱯឋ;DNAÁÂD┯஺ᦑ⌱.Ao1ஹᢣÃ:;Ḅ<=ஹ>ᜫᡈAᣚ஺2ஹḄwx.g%)¾ÄÅ஺3ஹḄᱯK.ᐹᨵOPឋஹL⚣ឋÆ}#Ḅ᳛LÈÉÃ}#ᦪᐸ᳛ÊËÌஹUVឋஹWᔣឋஹSTQᑭឋ஺⚪E⌕ὃḄÍ⌕Îὃ&ḄᭆÐ)¢ᳮ$Ò'ᔠᡠÍÔᑨᔜ⌱⚗×Ø)ᳮÙÚḄὃ஺35.ூᫀ௃Bூ᪆௃.জ«ÝÃḄ]^_!⁐ᓫ#%&ᱏßdᣚà%&ᙠ][!⁐#aD×Ø!⁐#᧕f;ঝ«ÝÃḄ]^_!⁐ᓫ#%&ᱏßdᣚà%&ᙠ[!⁐#aD×Ø56஺ᦑ⌱.B»᧕fãdᣚḄäÊ.জ᧕f×Ø!⁐#'᪀$ᙠåæçèéᑮ%&ᙠ][!⁐#aDdᣚ±²ᦋ!⁐#᝱ஹᜧìíᦪ*ᡠy!⁐#'᪀×Ø56ᙠåæçèéᑮî%&ᙠ[!⁐#Ḅ]^_!⁐ᓫ#aD஺ঝbcï24⚓ᐳ32⚓

24dᣚ[!⁐#\]^_!⁐ᓫ#aDefḄdᣚ᧕f;][!⁐#Ḅ]^_!⁐ᓫ#aDḄᱏßdᣚbᣚḄ]ef஺ঞ᧕f$%&Øᨵóᑖ)ᦪᑖ.bcdᣚô$%&ᙠᦪᑖõöÃ஺টøWù/yé¸᧕fãbcdᣚᙠú\û[Ḅü!⁐#Ḅã5ý஺⚪ὃ!⁐#'᪀ã56ḄûᐵÍᙠὃ&ḄÝ$)ᑨ$,ᵨᡠᔠᑖ᪆⚪Ḅ஺36.ூᫀ௃Cூ᪆௃Aஹᵫᐹᨵ!⚣ឋ$ᦑ&ᐭ()Ḅ3000*+,-./01234567$A┯9:Bஹ;<56ᙠ>ᦪᑖ@ḄABC$D,-./CEF&GḄHᨵIᑖ@$ᦑᙠ()C0456;<$B┯9:CஹJ5Ḅ./6KLMNO$4&GᨵIᑖ@$Ḅᭆ᳛RS$CTU:Dஹᐹᨵ02ᔣឋ$,-./C014W6⚜YḄZ[7$D┯9:ᦑ⌱Co1ஹHᢣC^_Ḅ`aஹbᜫᡈeᣚ஺2ஹḄghi5jklm஺3ஹḄᱯoᐹᨵpqឋஹ!⚣ឋrstḄ᳛!$u.vCstᦪ$ᐸ᳛xSyஹz{ឋஹ02ᔣឋஹ*|}ᑭឋ஺⚪ὃm.Ḅᐵ$⌕ὃ6m.ḄᳮஹஹZbo$ᔠ⚪CUᑨᔜ⌱⚗஺37.ூᫀ௃Cூ᪆௃Aஹ6ᱥtᑁᩩ⁐t*sᡈ}s$¡.ᓄ£⁐t᪀Ḅ7$A┯9:Bஹ¥ᙊ§¨x©ª§¨1©ᙊ§¨$¡£ᩖ¬.$Dᩖ¬.ḄᳮH;<$B┯9:CஹDNAᑖ/C^_Ḅ`aஹbᜫjeᣚ0123H$᝞56ᙠ®¯ṹ±$ᑣ³ᨵ´µ᪀Ḅᦋ$CTU:Dஹ·¸¹/¸º»$/¸¹/¸º»¼½ᔜ.¾7$£;<$D┯9஺ᦑ⌱Co¿⍡ÁḄ7ᒹÃஹ;ᦪÏ1Ðᑖ@ÑY$zḼ®ÊÓ⁐tiᵫ<ᔠ$®ÊÓ⁐tḄ®ÌÔiᵫ<ᔠ஺¬ÕÖᣚh>ᦪÏ1Ðᑖ@×YrØ

25ᑖty$zḼÊÓ⁐tḄ®ÌḄ¬ÕÖᣚD56;<஺Ù᜜$ÛEÜr᝞ÝÞßᳫÜáᓄâyjᙠkãäᵨrlByåÔW6;<஺r3y⁐t7ᒹÃ⁐t᪀7r;çஹbᜫஹ᧕Ìஹ᎔Ìyj⁐tᦪê7஺⚪ὃ6ᱥ7Ḅᐵ$⌕ὃ6Ḅᭆë$ìí¹ឋËᦋº»Ḅᐵî:;<Ḅïj⁐t7Ḅï$ᔠᡠḄUᑨᔜ⌱⚗஺38.ூᫀ௃Dூ᪆௃AஹóôᓄõḄ⍡Áö◤ᙠøὅúûCó$A┯9:BஹóôᓄõḄ5õ᳛◤ᙠkvCz{ó$B┯9:Cஹᙠúîóþ_ÿ
Ḅ⌕C┯DஹᓄḄ᳛=ὅᦪ+Ḅ!ᦪxlOO%,D()஺ᦑ⌱-D஺.⍡01ᨬ3⌱456᳛789:Ḅᓫ<=⍡0᝞⁐@ஹᓄABḄC⍡0Ḅ᳛ᑣEᙠ56G᪵⌱4Ḅ᪵I⌕JKḄLM⌕NO4᪵BḄC⍡0Ḅ⍡0PQᑣERὅSTUᓫVWXᯠZ[\]^_`ᑨb⍡0PQ஺I⚪ὃ.⍡0Ḅ7ᐵfg⌕hὃigj.⍡0Ḅᭆlஹ.mnopqr.⍡0Ḅ8snuvwᔠᡠzḄfg{)ᑨbᔜ⌱⚗஺39.ூᫀ௃Cூ᪆௃-AஹCᔲᝣḄ⍡0ᱥஹAL=ᨵᐵA()Bஹᐜᜩm21ᔠᝣ¡¢ᑗ7ᐵ¤¥〉¡§ᝣ7¨:¡§ᝣᡠi©᝕Ḅᐜᜩmi᳛9:B()Cஹ⍡0«¬§®¯bC.⍡0°±ஹ⚜■Ḅ´⌕µ¶·¸v¹ᶭ¹ᶭ⍡0C┯Dஹᓽ¼)½¸¾¿À<=·Áᨵ¤vÂ⁐ÃÄ⍡0D()஺ᦑ⌱-Co⍡0Ḅ°±⚜■-1§®¯b-\i®ÆiᵨÈÉḄʱµ¶)½CᔲË⍡0ᡈᐜᜩឋΧ®¯b¤RᜧᜧÐÑḄ\i᳛஺2⍡0«¬-ᙠÒ½ḄÓÔÕvKᨵᦔḄ⚜■⍡0Ḅ§i×஺3ἭÙÚÛwÜ஺I⚪ὃ⍡0Ḅ°±⚜■⌕hὃigj.⍡0Ḅ.mnopqr°±⚜■.⍡0ḄÝÞvwᔠᡠzḄfg{)⚪஺40.ூᫀ௃Bá26⚓ᐳ32⚓

26ூ᪆௃-Aஹᵫoåwæ¤fᜐᳮ1éêëìḄíÔîïðñLòḄóô᳛A()Bஹ=ôõCLòḄóô᳛öôõCêëìᜐᳮ1éêëìḄíÔB┯Cஹêëìᜐᳮ÷ḄøùvóúÂ⁐ᦪûüòýᳮCêëìvᢓᑴ
ᑖ┴ḄᡂCDஹ␺₝⃉Ḅᨬ☠Ḅ
Ḅ⁐ᦪᨬ"#$#%⁐Ḅ᝱ஹᦪ'ᨬ(ᨎD஺ᦑ⌱-Bo᪷/⚪1234ᑖ᪆6-789ᵨ;8<=>?@AᜐᳮDḄEF᳛;8>?@A8H<=ᜐᳮ;89DḄEF᳛I;8஺ᐸᙠᵨ>?@A<=$0.2%ᜐᳮ1ᜩḄMNOEFᡂḄPḄᦪ'ᨬD஺Q⚪ὃSDTUஹVWᑖ᪆X7ᐵ6Z1ᙠὃS[\ḄZ32ᑨ^_`ab᫏⚪஺41.ூfᫀ௃Dijkl⁐lmijnopqrpstuvw>?@Arxyᜐᳮtᜐᳮz{ḄU|ஹ}~ᡈDUḄឋᙠHᙢTU▲ூ᪆௃-1ஹᩖTUḄᳮijnoᐸ;8Ḅឋb8Hᓫ⚜஺2ஹElTUḄᳮijklᵨᱥᳮjAr᝞X¡ஹ¢¡ஹ£᜜¡ஹ¥ᐝXtᡈᓄ[jAr᝞¨©⏚ஹ«⏚¬®Xtᩭᜐᳮ\ᱥ°ᐸᙠ
ᑖ9#DNA±ᑴ{\³┯µ¶·ijklᐸ¸¹lm⚣᳛»¼½ឋᜧ¿=ᦋÁÂឋÃÄTUÅÆ஺3ஹᓫTUḄᳮ⁐lmᵨpquvwÇÈᓫÉÊËÌÍEF⁐ᦪ'ÃÎᔠÐÑÒ;{\ឋᑖuj¶_TU▲஺4ஹDTUḄᳮ⁐lmᑭᵨ>?@Aᜐᳮz{ḄU|ᡈ}~ÔÕÖ×ØᱏஹÚV2U|ÛÜÝᜧÞß2àáâX⃩wᱥâḄäåÛᨵᡠèÃ஺5ஹijÍÆTUḄᳮijno_ᢥ᯿ÌëḄ1ìᔣᦋ⌼\ᱥḄឋ஺ᦑfᫀ$-r1tDr2ijkl3⁐rᦪ'tlm4ijno5pqrpstuvwr6>?@Arxyᜐᳮtᜐᳮz{ḄU|ஹ}~

27r7tᡈDUḄឋᙠHr8tᙢTU▲TUḄÜÝ-ᩖTUElTUDTUᓫTUᜐᩖHÐHᵨ¡ஹ¥ᐝஹᓄ[qᵨ>?@Aᜐᳮz{pquvwᳮ⌱TÐᱥᜐᳮÑḄU|ᡈ}~EFpsõö{ẚô┴ḄᡂijnoÌÍE{ijklTËᵨ>?@Aᳮ°⁐ᦪ'ÃᜐᳮᓫÃÄTUᦋឋᘤøᜧ⃩wᱥâäTU▲ùú⚜ùᕜùᨵᑭ;D◤ᜧå¹ù{Týþ±ᩖᡂÿ᳛
ᜐᳮ᳛⚪ὃᙠὃὃᳮᡠ⌕
Ḅᳮ!ὶ#▭%ᔠ'ᵨᡠ)*ᯠ,-./01Ḅ23ᱥ5⚪஺42.ூ;ᫀ௃>?ᓿABCcdḼGHᑖJKLM⁐ᓫPᑖQRᦪᑖJIUVWXM⁐PḄ*ᵫZᔠ-RᦪᑖJὶ/[WXM⁐P\VKLM⁐ᓫPḄ]ᣚ_`a]ᣚb63eḄPBC1Ḅ63ᩩM⁐Pᐸ132ᩩᩭ*i31ᩩᩭ*klᨵWXM⁐PnoRᦪᑖJpq1rstWXM⁐PḄὶ/tunovBCrwᡂ,ᜧ{e|}vU~ூ᪆௃_1bBWXM⁐PᑖQBC|ᙳᑖJu>?ᓿABCBCᩩM⁐P\ᨵ2ᩩM⁐ᓫPᨵ2DNAᑖᜐ1cd஺_2b1dewᡂḄḼGHᑖJKLM⁐ᓫPᑖQᩩM⁐PḄDNAᵫ2u1஺_3b“wᡂ”2☢⌕ᭆ¢⍡¤¥᪵ឋḄwᡂRᦪ¨2©ᑖJUVWXM⁐PḄ*ᵫZᔠ-RᦪᑖJὶ/[WXM⁐P\VKLM⁐ᓫPḄ]ᣚ_`a]ᣚb஺_4bei-kᨵឋᩖ`Ḅ«ᱥi-kḄᔠwᡂḄ¬ᓿ®¯ᩭḄeḄPBC1ᨵ63ᩩM⁐P஺°Ḅ±vBC|®²³ḄRᦪᑖJ|}vU~஺RᦪᑖJ1M⁐PtuḄ´µ¶ᐸeḄPBC1Ḅ63ᩩM⁐Pᐸ132ᩩᩭ*i31ᩩᩭ*klᨵWXM⁐PnoRᦪᑖJpq1rstWXM⁐PḄὶ/tunovBCrwᡂᜧ{e|}vU~஺ᦑ;ᫀu_1b>?ᓿABCcd_2bḼGHᑖJKLM⁐ᓫPᑖQ¨28⚓ᐳ32⚓

28(3)Rᦪ¨2©ᑖJUVWXM⁐PḄ*ᵫZᔠ-RᦪᑖJὶ/[WXM⁐P\VKLM⁐ᓫPḄ]ᣚ(`a]ᣚ)(4)63eḄPBC1Ḅ63ᩩM⁐Pᐸ132ᩩᩭ*i31ᩩᩭ*klᨵWXM⁐PnoRᦪᑖJpq1rstWXM⁐PḄὶ/tunovBCrwᡂᜧ{e|}vU~ᑖ᪆⚪ᵬBCᑁ|WXM⁐PuvBC¿|WXM⁐PḼGH᣸ᑡᙠBC1ÂuRᦪ¨Ã©ᑖJ1¿BCWXM⁐PᑖQBC|ᙳᑖJu>?ᓿABC஺⊤ÅBCᑖJpq2ᩩM⁐P\DNAᦪḄÆᓄbewᡂḄDNAḄÉᑴ¿cd⊤ÅᨵGᑖJË-1ஹRᦪ¨2©ᑖJஹRᦪ¨Ã©ᑖJË-1¿dewᡂḄḼGHᑖJ¿ef⊤ÅᨵGᑖJU-ÎஹRᦪ¨Ã©ᑖJU-Î஺⚪ὃÏᨵGᑖJ-RᦪᑖJᙠὃὃḄÐ-ᳮѵ〉1஺43.ூ;ᫀ௃2ஹ3ஹ4ÓÔÕῃ×᪶ᵞ⏚aஹd]⊡ÝÞßàá]⊡âãßãÉᑴ-äåᶇÉᑴß⏘-DNAèᔠ⏘ூ᪆௃(1)2᪶ᵞ⏚ᒹ¢2ᑖê⏚2ᑖῃ×᪶ëஹ2ᑖàáᵬ1ì⊤Å2᪶ᵞ⏚ḄᦪíZᔠ2ஹ3ஹ4,᪷ïðàáḄñò᪶ᵞ⏚uÓÔÕῃ×᪶ᵞ⏚஺(2)ᵫÅ-DNAᑖäåᶇÉᑴpqì1DNAᑖÉᑴḄóôõaõ-dõ᪷ïàá]⊡âᑣóôõaஹd1Ḅàá]⊡â¯÷ᔠᡂḄõbøcᑖùøaõ-dõ]⊡â{÷ᔠᡂḄõbøc]⊡஺(3)DNAᑖÉᑴḄpq1ᐸúᱯḄÝÞß᪀uÉᑴýþÏÿḄ
⊡ᑣᜧᑴḄឋ஺(4)DNAᑴḄᱯ$ᨵ&'(&ᑴ)*ᶇᑴᑴ,◤⌕Ḅ⏘ᨵ'(⏘)DNA0ᔠ⏘஺ᦑ3ᫀ56(1)2ஹ3ஹ4;<=ῃ?᪶ᵞ⏚(2)aஹd⊡(3)EF(⊡(4)&'(&ᑴ)*ᶇᑴ'(⏘)DNA0ᔠ⏘ᑖ᪆⚪J6Jᵬ5DNAᱏMḄN᪀Jᐸ,1QR⏚2Qῃ?᪶S3Q;T=2ஹ3ஹ4Uᡂ;T=ῃ?᪶ᵞ⏚஺JWX᧜ḄQDNAᑖZḄ*ᶇᑴ[aஹd5
[[bஹc5^ᔠᡂḄZ[஺_⚪NᔠDNAᱏMḄN᪀J`⌕ὃbDNAᑖZN᪀Ḅᱯ$)DNAᑖZḄᑴ⌕cὃdefDNAᑖZN᪀Ḅ`⌕ᱯ$)DNAᑖZᑴgᑨiJ,ᔜN᪀

29ḄklmNᔠᡠoḄpe3⚪஺44.ூ3ᫀ௃X◚ឋXAXa1-2u1vwxyzᨵᦋ|}~⍡ᱥூ'᪆௃'61ᵫᑖ᪆p}QX⁐Ḅ◚ឋ}஺2ᵫᑖ᪆pII-2Ḅ}~5XAX}51-2Ḅ᱄1-1⊤w}~5XAY,ᦑpII-2Ḅ1-2Ḅ}~5XAXa,ᑣH-6Ḅ}~5XAxaᡈXAXA,᪷J)⚪11-4Ḅ}~}H-2}~¡¢Ḅ£ᨵ1-2¤஺ᵫᑖ᪆pH-1Ḅ}~QXAY,II-2Ḅ}~QXAX,ᡠdZ᝕,ᨵ᝞§¨©ª~6xAxA,xAx\XAY,xaY,«¬5i6i6i6i,}n-i)n-2d¤v®¯ZḄᭆ᳛543U-6}~56XAXAஹlxAXSwᵱឋXAY³´µ®Ḅᭆ᳛5:22211x—=0484xy·ᶭ¹º»¼§½ᑮ¿'ÀÁzᨵᦋ|¤Ḅ}~⍡ᱥ}©Ã5xyÄ⊤~Ḅᦋ|´µÅᯠǽᑮ}È®ᓽº»¼§ÅÇ⍡Ê´µᦑËvw஺ᦑ3ᫀ561X◚ឋ32XAXa1-234314vwxyzᨵᦋ|}~⍡ᱥ᪷JÌpn-i)n-2ÍwdÎᨵḄÏZni-i)m-2,}ᑨiQ◚ឋ⍡ᵫ◚ឋ}ÐᑴÑNᔠ⚪ËH-1vÒÓ}ᓾdήḄÏZ,ËÖ}Qx⁐Ḅ◚ឋ}n-iḄ}~QXAY,n-2Ḅ}~QXAX%_⚪Nᔠ×ØJὃbÙឋ⍡)×ØJ,⍡ÚÛḄᑨi'3_⚪ḄᐵÝᙠNᔠ⚪)×ØJᑨiÎḄ⍡ÚÛ)ßᑖ¤Ḅ}~ÁgNᔠ⚪àá3஺45.ூ3ᫀ௃¡¢ᡠᵨḄ
¡¢ãäbஹaåṹZḄçÁឋᙠg■éᵫᦋ|ÈÄḄdᱥឋêḄᦋ|e⌮ìíXìí⏘ூ'᪆௃'61J1,ᨵî¤᪶SïðJÌḄñᐰñᡂ´î¤᪶SᔠᡂḄóôQ¡¢Ḅ}5î¤᪶SᡠᵨḄ
mRNA¡¢஺2J2ᡠÌḄQãäḄõᡠQb᪶SöᱥQa÷[©ø⏚gᨵù¤åṹZÂúûüåṹZḄçÁឋðåṹZ,ᨵ¤ᦋ|ýᵫþ30⚓ᐳ32⚓

30ṹḄឋᦋᐸḄ⏚ᙠ■"ᵫ$ᦋ%&'Ḅ(ᱥឋ*Ḅᦋ஺(3)/11᪾ᑁᡠ5(ᳮ789:7;/3<Ḅe7>?/3?ᡠᵨḄLM>?(2)9:bஹaṹRḄឋᙠ■"ᵫ$ᦋ%&'Ḅ(ᱥឋ*Ḅᦋ(3)e⌮BC(FBC)⏘ᑖ᪆/1J/1⊤5VBCV9:78W᪶YZᱯᨵḄ1]஺ᑖ᪆/2J/2⊤59:7ᐸḄ⏚ad8mRNA,d9:ḄLM஺ᑖ᪆/3Ja8DNAᑖRrᑴ7b8BC7c8⌮BC7d8RNAᑖRrᑴ7e89:7஺t⚪vᔠ/xὃz⍡|}~ḄBC9:⌕ὃ(l⍡|}~BC9:Ḅ7ஹeᡠஹᩩᱥᑨ/57ᱥḄvᔠᡠḄlH⚪஺46.ூHᫀ௃ᵫᔠᑖm?⁐cAABBxaabb1AAbbᡈ5aaBB¡⁐¢J£⁐¢=1J1ூx᪆௃xJ(1)¥⚪¦<“¨©cᔁ«¬Ḅ¡⁐¢£⁐¢8ឋ®ᑴ¯>ឋ*Ḅ°(AஹaBஹb)ᑖm3±8±⁐c”°´µ?⁐cḄµ°ᡠ¶ᔁ«¬¢⁐ឋ*Ḅ⍡|⍳¸Ḅᵫᔠ¹஺(2)ᔠজF?<¡⁐¢J£⁐¢=15J1,ᵫ¾¿À£⁐¢ÁÂdÃ◚ឋᐸÅᙳ8¡⁐¢ÁÂÇBÈ8AaBb,ᑣÊtÈ8AABBaabbaᳮËᔠজḄ15F2¡⁐¢ÁÂḄÈ8A_B_ஹA_bbஹaaB_,ᐳᓰF?ÎḄ,ᐸ<ÏᔠRᨵAABBஹAAbbஹaaBBᐳᓰF2ÎḄt,ᦑᳮËᔠজḄF2¡⁐¢ÁÂ<ÏᔠRᡠᓰḄÐÑ(3)ᔠঝF2<¡⁐¢J£⁐¢=3J1,¿ÀBÈ8AabbᡈaaBb,ᑣÊt<¡⁐¢ÁÂḄÈ8AAbbᡈaaBB«ÔᔠঝḄF,AabbᡈaaBb;£⁐¢ᔁ«¬ᩖÖᳮË×ÎḄ⊤ÈÐÑ8¡⁐¢J£⁐¢=1J1஺(4)ᔠজḄHcYZḄÈ8AaBb,ᐸ5Ù/᝞Û:

31(1)ᵫᔠᑖm?⁐c(2)AABBxaabb1(3)AAbbᡈaaBB¡⁐¢J£⁐¢=1J1᪷¥⚪Ù/⊤ᑖ᪆JᔠজF2<¡⁐¢J£⁐¢=15J1,d9J3J3J1Ḅ]ᵫ¾¿À£⁐¢ÁÂdÃ◚ឋᐸÅᙳ8¡⁐¢ÁÂÇBÈ8AaBb,ᑣÊtÈ8AABBaabbaᔠঝF?<¡⁐¢J£⁐¢=3J1,¿ÀFiÈ8AabbᡈaaBb,ᑣÊt<¡⁐¢ÁÂḄÈ8AAbbᡈaaBB஺t⚪vᔠ/⊤ὃzᵫᔠ¹ᵨÙᙠὃzὃ(ᑖ᪆⊤àáâᨵᦔ}~Ḅäᑨänᵨᡠlåᔠᑖ᪆æ⚪xçæ⚪Ḅä஺è32⚓ᐳ32⚓